Irisin, named after Iris, the Greek goddess of the rainbow, was first described in 2012 by a research team led by Bruce Spiegelman of Harvard University. Her discovery caused a sensation in the scientific world, as it revealed the existence of a hormone that acts as a relay between muscles and other organs during exercise. The name "rainbow hormone" seems to be an apt reflection of its versatile properties - irisin connects the body's various systems, harmonizing their functions like the arc of a rainbow in the sky.
Mechanism of action of irisin: exercise adaptation hormone
Irisin is secreted as a result of skeletal muscle activation during exercise. Its main source is the fibronectin type III domain-containing protein 5 (FNDC5), which undergoes proteolytic conversion under the influence of movement, releasing irisin into our circulatory system. But how does...
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