Today will be about the "secret hormone", which I am sometimes asked about by patients, and also sometimes by colleagues interested in the topic of weight loss who have other specialties.
rT3 is part of our hormonal endocrine puzzle, and knowing that the hormone exists can help explain many situations related to our health, especially if we are experiencing weight loss problems, fatigue, sluggishness, impaired concentration, and even full-blown symptoms of brain fog. A person with an elevated rT3 concentration may even have an ideal TSH, and may complain of fatigue, and this does not at all mean that such a person is lying.... It is then worth ordering a determination of reverse triiodothyronine (rT3, reverse T3), which is the inactive form of the hormone triiodothyronine (T3), one of the main hormones produced by the thyroid gland. Triiodothyronine (T3) and thyroxine (T4) are key hormones responsible for regulating metabolism in the body. rT3 is formed from thyroxine (T4) by enzymatic conversion, which occurs mainly in the liver, kidneys and other peripheral tissues.
So what is the function of rT3 in our body?
It's worth realizing that rT3 is a metabolically inactive metabolite, meaning that it doesn't affect metabolism the way the active form of T3 does. Rather, it acts as a regulator, blocking receptors that would normally be activated by T3. In ...
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