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Diagnostics of the future: mass spectrometry in detecting difficult-to-diagnose diseases

MedExpress Team

Medexpress

Published Nov. 27, 2024 13:26

Diagnostics of the future: mass spectrometry in detecting difficult-to-diagnose diseases - Header image
Autorstwa Panek - Praca własna, CC BY 3.0,
Endometriosis, lung cancer and breast cancer are just examples of diseases that are difficult to detect, and the comfort and sometimes the life of the patient may depend on their diagnosis. Scientists at the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences can help speed up their diagnosis. - For the specific needs of doctors, companies or scientists, we are looking for markers and developing diagnostic panels, they say. And they are already developing a panel for endometriosis together with Prof. Piotr Laudanski of the Faculty of Medicine at WUM.

- We are developing a diagnostic test that is both sensitive and reliable, yet minimally invasive. It's a diagnostic panel that takes advantage of the benefits of mass spectrometry and can be carried out from a blood sample, even in young girls who have not yet had intercourse. Its proper design requires a properly planned study on a sufficiently large group of patients, says Professor Piotr Laudanski of the Department of Obstetrics, Women's Diseases and Gynecology Oncology, Faculty of Medicine, WUM.

Endometriosis is one of the diseases that can be effectively and accurately diagnosed in its early stages. According to WHO data, this affliction affects 190 million women and girls worldwide, and in Poland up to one in ten Polish women of reproductive age. In many cases it leads to infertility, but above all it is a source of pain that is difficult to control. Due to its location - deep in the abdominal cavity - and the dependence of symptoms on the hormonal cycle, it often takes many years until a diagnosis is made, during which women suffer and their bodies undergo - sometimes irreversible - changes.

- We have already collected results from plasma analyses of a group of patients, but we plan to confirm the effectiveness of our ...

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