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Systemic lupus erythematosus - multiple organ complications, increased mortality, and high medical and social costs

MedExpress Team

medexpress.pl

Published April 26, 2023 09:49

Systemic lupus erythematosus - multiple organ complications, increased mortality, and high medical and social costs - Header image
Continued education of physicians of various specialties and the introduction of systemic changes to improve the diagnosis of systemic lupus erythematosus (TRU) and improve access to effective therapies are the main recommendations of rheumatology specialists. A set of guidelines, aimed at improving the care of patients with this severe condition, is included in the Report "Systemic Lupus Erythematosus. Medical and Social Aspects of the Disease and Treatment Strategy," prepared by the Polish Society of Rheumatology.

The report was premiered at a press conference held at the PAP Press Center on April 21, 2023. The report received the honorary patronage of the Patient Ombudsman.

Systemic lupus erythematosus(TRU; SLE) is an autoimmune disease in which more organs and systems are affected and their functioning deteriorates. The joints, muscles, skin and kidneys are most often affected, as well as the cardiovascular, central nervous, hematopoietic and coagulation systems. However, the symptoms of TRU are nonspecific and different in different patients, and such a diverse clinical picture of the disease, which is not fully reflected in the classification criteria, poses a real diagnostic challenge.

- The heterogeneous clinical, laboratory and immunological picture of the disease creates great difficulties at the initial stage, when individual symptoms, such as those of the skin, joints, kidneys or hematology, may be treated by doctors of different specialties as unrelated. The eligibility criteria for TRU do not cover all possible symptoms of lupus, so if the disease starts with those not included in the criteria for early diagnosis can be difficult. Specialized rheumatology centers should have system tools for rapid diagnosis, because they have the most knowledge and experience," she said. Prof. Maria Majdan, head of the Department of Rheumatology and Systemic Connective Tissue Diseases in Lublin..

Significantly, the mortality rate of patients with TRU is 2-3 times higher compared to the general population. The disease is also one of the leading causes of death in young women, who develop lupus more often than men. Active disease often prevents them from becoming pregnant and giving birth. Patients, as a result of chronic fatigue and other ailments resulting from the disease, are often forced to give up their previous social, professional and family lives. The longer the disease lasts and the longer it remains highly active, the greater the risk of comp...

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