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The future of SMA treatment brings positive changes and new therapeutic options

MedExpress Team

medexpress.pl

Published Sept. 17, 2024 09:03

The future of SMA treatment brings positive changes and new therapeutic options - Header image
Five years of experience, related to the functioning of the drug program in Poland, concerning the treatment of SMA, confirmed that we are dealing with a model solution. This does not mean, however, that there is no room for change. The first ones have already occurred and concerned pregnant women. More could follow with the availability of a higher dose of nusinersen and the introduction of a new route of administration. An entirely new molecule is also in development. For now, however, we must wait for the results of clinical trials and relevant registrations.

Positive changes in drug program for women with SMA

An important change introduced in the drug program B.102.FM. "Treatment of patients with spinal muscular atrophy," took effect on April 1, 2024, and applies to women with SMA who want to have offspring. The Ministry of Health has decided to continue nusinersen treatment during pregnancy. The changes introduced meet the existing needs of adult SMA patients, who previously had to discontinue treatment during pregnancy, which was associated with a worsening of their condition. The current decision will improve the quality of life of patients with spinal muscular atrophy who choose to become mothers.

- The drug has been registered very broadly from the beginning for the treatment of SMA regardless of the patient's age or the copy number of the SMN2 gene, which is the most important factor modifying the rate of disease progression. In terms of the drug's use in pregnant women, the drug's product characte...

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SMA

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